Liver transplantation is the only curative treatment for end-stage liver disease. We present the outcomes of 521 liver transplant recipients at our center. 544 liver transplants were performed between December 2006 and January 2013. Living donor grafts were used in 399 first transplants (77%), 287 of which were right lobe grafts. 23 patients required a re-transplantation Mean recipient age was 48 years (range: 18-71 years) for adults and 54 months (range: 5-17 months) for children. Mean MELD score was 17 and mean PELD score was 16. Viral hepatitis B (36%) was the most common cause for liver transplantation in adults. Cholestatic liver disease was the most common cause in pediatric recipients. 21 transplantations were performed due to fulminant hepatic failure. Four patients died during the operation and 39 patients died in the early postoperative period. Median hospital and intensive care unit stay were 15 and 2 days, respectively. Mean follow-up was 23 months (range: 6-79 months). Hepatic artery thrombosis (1.4%), portal vein thrombosis (2.2%), biliary leak (10.3%) and biliary stricture (14%) were the main surgical complications observed. Overall survival was 82%. Our results are acceptable for a high volume transplantation center. Close follow-up and a multidisciplinary approach are key to success