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Volume: 6 Issue: 4 November 2008 - Supplement - 1



In the recent past, chronologic age was a contraindication both for organ donation and transplantation. But, the rapidly growing number of patients with end-stage renal disease are increasing everywhere in the world. Moreover the extreme organ shortage in Turkey has been leading us to use expanded living or diseased donor. We retrospectively analyzed Gazi University Medical Faculty transplantation registry and patient data to determine old donor’s outcome. Since 1996, totally 193 renal transplantations were performed to 191 renal recipients. Sixty out of 193 were from deceased, 133 were from living donor. Totally 25 (7. 7%) out of 193 donors were at the age 55 years old or older. In this group 15 out of 25 donors were from living, rest of were from diseased donor. Mean cold ischemia time was 4.5 hours (range, 1–24 hours). The immunosuppressive protocol consisted of induction therapy (Simulect 20 mg days 0 and 4) and triple immunosuppresion (calsineurin inhibitors, mycophenolic acid and steroids). Mean hospitalization time was 25 days (range, 9–35 days). Nine patients (3.6%) presented DGF requiring transitory hemodialysis. One patient lost her graft due to BK infection. None of the recipients or the grafts was lost due to any surgical complications. We have seen 3 acute rejection episodes. All were reversed by pulse steroid. Although 4,2% of recipient had DGF, it did not affect graft outcome respectively. Mean creatinine levels for 1 and 3 years were 2.1 and 2.3 respectively. Patient and graft survival for 1, 3, 5 years are 100%, 96%, 86% and 100%, 96%, 82% The use of old (>55 years old) donor kidneys may associated with worsen renal function and reduced graft survival compared with standard donors. Kidney transplantation from old donors should be considered as option for kidney transplantation.

Volume : 6
Issue : 4
Pages : 72

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General Surgery, Gazi University Medical Faculty, Ankara, Turkey