Infection is an important factor of morbidity and mortality after heart transplantation (HTx). We aimed to investigate the infectious complications and associated factors in heart transplant recipients. All patients that underwent HTx at Baskent University Hospital from March 2004 to January 2008 have been included in the study. The patients’ data was retrospectively reviewed from their charts. Their post transplantation infectious complications were evaluated in regards to time of onset and causative agents. There were 19 patients undergoing HTx. Fourteen patients (73.7%) were male. Their mean age at the time of transplantations was 30.5 (range: 12-55) years. The indications for HTx included 10 (27.0%) dilated cardiomyopathy, 4 (10.8%) ischemic dilated cardiomyopathy, 3 (8.1%) congenital heart diseases, 1 (2.7%) restrictive cardiomyopathy, and 1 (2.7%) familial cardiomyopathy. There were 30 episodes of infection in 14 of the patients (number of episodes were 1 in 5 patients, 2 in 6 patients; and the remaining 3 patients had 3, 4, and 6 episodes). The onset times of the infections after the transplantation were less than a month for 11 (36.7%), from 1 to 6 months for 15 (50%), and more than 6 months in 4 (13.3%) of them. Causative agents were identified in 60% of the bacterial infections, and in all of the urinary tract infections. Bacterial infections were more common then viral infections after HTx. Bloodstream infections were dominant during the first month after the HTx, and pneumonia was the overall most common infection.