Increased incidence of infections and malignancies is unavoidable consequence of immunosuppressive treatment after organ transplantation. Dermato­fibrosarcoma protuberans (DFSP) is a relatively uncommon spindle cell tumor of the skin that has a propensity for local recurrence but rarely metastasizes. This case report describes a 35 years old man with local recurrent dermatofibrosarcoma of the chest 3 years after receiving a kidney from living unrelated donor. Interestingly, he had a history of successfully treated the tumor 17 years without evidence of tumor recurrence before transplantation. The tumor was resected by removing the mass of the chest. Unfortunately, local recurrence was seen one year after the tumor resection and cessation of cyclosporine; he went on hemodialysis 8 months following repeated relapse. To our knowledge, this case represents the first report of recurrent fibrosarcoma following kidney transplantation in Iran. Early diagnosis and prompt wide local resection of this tumor are required in order to prevent a local recurrence.