Children with chronic kidney disease are often growth retarded. Most of the children have good weight gain after successful kidney transplantation but height gain is not satisfactory mostly for children who are transplanted in older age. This study was conducted for evaluation of growth and BMI in children following kidney transplantation. All children who had been transplanted in our center and had regular follow up were encountered in this study. Those with primary non-functioning grafts were excluded from the study. Weight and height at transplantation and at their last visit were recorded and for those with ages lower than 20 years WHO percentile curves of BMI were used for evaluation and those older than 20 were evaluated according to normal adult values.SPSS15.1 soft ware and paired T-Test were used for comparison of means. One hundred and thirteen children were involved in this study. Mean age at transplantation was 13.2 ± 5.6 ranging from 3 to 22 years and age at last visit was 18.3 ± 4 years. They had been followed from 6-180months (Mean 61 ± 38 months). Their primary renal diseases were as follow: Reflux-obstruction dysplasia47, hereditary 36, glomerular disease22, unknown and missing 7 and stone 1. Mean pre-transplant body weights, height, BMI were significantly different from post-transplant values: 31±11 kg, 135 ± 20 cm, 17 ± 3.5 kg/m2 vs. 46.6 ± 12.6 kg, 151.5 ± 12.5 cm, 20 ± 3.95 kg/m2 (p<0.001). Latest serum creatinine was1.24 ± 0.6 mg/dl ranging from 0.5-4.1mg/dl. Pre and post-transplant percentiles of BMI were significantly different (33.6 ± 34 vs. 40 ± 31) p<0.001. We can conclude that despite short period of follow up kidney transplantation has a dramatic effect on growth and BMI of children.
Volume : 6
Issue : 4
Pages : 217
Shiraz Transplant Center, Namazi Hospital and Nephrology Urology sResearch Center, Shiraz University of Medical Sciences, Shiraz, Iran