As the population ages, clinicians have seen and will continue to see elderly patients suffering from end-stage renal disease (ESRD) requiring renal replacement therapy. There were limited studies in the MESOT countries for determining the influence of recipient age on outcome after renal transplantation. We therefore retrospectively reviewed the medical records of two center databases to ascertain the clinical outcome of live kidney transplantation in elderly patients. This study involved 380 kidney allograft recipients (259 men and 121 women), transplanted between September1986 and January 2007. Recipients were defined as "elderly" if they were 60 years of age or older. The most common cause of ESRD was diabetes mellitus, followed by hypertension. The mean ages of recipients and donors were 69 ± 8 and 27 ± 7 years, respectively. The majority of patients received living unrelated donor (LURD) kidneys (82.9%). The median serum creatinine level of our patients in the last visit was 1.56 mg/dL. The clinical outcome was promising in studied elderly patients, the occurrence of graft loss was only 15.3 %( n=58) and 9.7 %( n=37) of cases died in the follow up period. The prevalence of hepatitis B and C among our recipients were low, HBsAg and HCV antibody were only positive in 5 (1.3%) and 11 (2.9%) of cases, respectively. In conclusion, our results confirm that renal transplantation should be considered for selected patients older than 60 years requiring renal replacement therapy.