This is a prospective cohort study in post-renal transplant who fasted 3 consecutive Ramadans. The baseline eGFR, mean arterial pressure (MAP) and urinary protein excretion before the first Ramadan were compared to those after the 3rd Ramadan in 35 the fasters and 33 non-fasters. The effect of age, duration post-transplant, presence of diabetes mellitus (DM) and proteinuria on changes of the GFR were studied The two groups were comparable in gender, age, transplant type, duration post-transplant, presence of DM, hypertension, proteinuria, serum creatinine and MAP. Among the fasters, there was no change in eGFR following 3 Ramadan’s fasting (56.4 ml/min ml versus 55.4 ml/min, respectively, p= 0.8) even after adjusting for age, DM, baseline GFR, proteinuria or duration post-transplant. Comparing between fasters and non-fasters in the changes in GFR, MAP and urinary proteinuria excretion between baseline and the 3rd Ramadan, we found the differences not to be significant.