The majority of transplantation activities are solely dependent on cadaveric organs. In recent years, special attention has been paid to brain dead patients in Iran but it is not clear if such attention has helped in increasing cadaveric organ donation or not. Our data come from Organ Procurement Unit of Shaheed Beheshti University of Medical Science. It is the biggest and most active organ procurement unit from brain dead patients in Iran. All data regarding organ donation from brain dead patients from 2004 was evaluated for analysis. We describe demographic characteristics of the patients along with data regarding brain death and organ donation. In the specified period 93 brain dead patients were registered in database. The mean age of the patients was 31.7 ± 15.5 (range: 4 to 76) years and 64.5% of the patients were female. The cause of death was trauma (57%), vascular aneurysm (19.4%), drug toxicity (7.5%), tumors (5.4%) and other causes (10.7%). 84.6% of the patients successfully donated their organ(s), 14.3% expired eventually before donation and 1.1% had no suitable organ. Harvest rate of different organs were as follows: kidneys (73.1%), liver (66.7%), heart (41.9%), cornea (11.8%), pancreas (5.4%), lung (4.3%) and bone (2.2%). We observed an overall satisfactory harvest rate from brain death patients; however, we believe that it should be improved. Kidneys and liver were the most frequently harvested organs while lung and bone were the least frequent ones and should receive more attention.