There have been conflicting reports that kidneys from small donors may be at risk for graft loss if they are transplanted into large recipients. The aim of this work was to examine the impact of Donor/Recipient Body Weight Ratio (D/RBWR) on allograft outcome. 217 kidney transplant recipients were selected and all patients achieved of five years follow up. All patients received kidney from living unrelated donors. Immunosuppression consisted of cyclosporine A, mycophenolate mofetil (or azathiopurine) and prednisolon. According to D/RBWR patients were divided into 3 groups: low (less than o.8 G1), medium (0.81-1.1 G2) and high (more than 1.1 G3). One, three and five years graft survival, episodes of acute rejections and means of creatinine was recorded. Among patients 126 (58%) were female. Mean age was 41.62 years.There were no statistically significant difference in the incidence of acute rejection episodes, means of creatinine and one, three and five years allograft survival between groups.(Table1). We conclude that low Donor/Recipient Body Weight Ratio has no effect on short and long term renal allograft survival.
Table1: Allograft survival rates among different groups
G1 | G2 | G3 | ||||
1 year graft survival | 92.62% | 91.41% | 90.22% | |||
3 years graft survival | 81.21% | 80.34% | 79.23% | |||
5 years graft survival | 69.46% | 66.93% | 70.17% |