The population of elderly people with chronic renal insufficiency is increasing around the world. It has been shown that renal transplantation may be the best treatment for these patients. However, it has been observed that older patients who have received a renal transplant (RTX) have a higher mortality rate associated with infections than those who are younger. This study was aimed to evaluate renal transplantation in recipients over 50 years of age. Six hundred fifty renal transplantations were performed at Imam Reza hospital from 1989 to 2002 out of witch 83 were done in patients older than 50 years (50 to 66). We determined one year, three years and five years survival and the prevalence of hypertension, hyperlipidemia, and urinary tract infection (UTI) after transplantation. Rate of patients survival at 1, 3 and 5 years after renal transplantation were 92.4%, 84.7% and 75.5% respectively. 80% of recipients had hypertension after transplantation and 67.1% had UTI. Cholesterol level was high in 55.4% of recipients and hypertrigliceridemia occurred in 70.8% of patients. Actuarial evaluation showed no relation between one year, three years, five years survival and the three complications (hypertension, hyperlipidemia, UTI). There was no correlation observed between age and sex of recipients with the three major complications. It seems that renal transplantation can be performed safely and with acceptable prognosis in the elderly patients after clinical evaluation.