Renal transplant recipients (RTRs) are predisposed to a variety of cutaneous complications due to immunosuppressive therapy. We aimed to determine the incidence and the clinical manifestation of skin diseases in these patients. Ninethy RTRs (51 males and 39 females), aged 15 to 58 years (mean: 36.42±11.90), with mean interval after kidney transplantation (RTX) of 23.05±19.48 months were consecutively examined as outpatients. The effects of age, sex and duration time after transplantation on cutaneous manifestations were evaluated and the dermatologic manifestations in RTRs were compared with control group consisting of 90 persons. The immunosuppressive regimen consisted of cyclosporine, systemic corticosteroids, mycophenolate mofetil. sixty two patients (68.8%) had skin manifestations, 52 patients (57.7%) had drug-related manifestations, including acneiform eruption (n=43), gingival hypertrophy (n=18), hypertrichosis (n=49). Cutaneous viral infections identified in 20 patients (22.0%) included verruca vulgaris (n=9), herpes zoster (n=5) and herpes simplex (n=6) &Human papilloma virus (HPV) (n=11). 3 patients (3%) had premalignant or malignant skin lesions. Fungal infections, consisting of dermatophytosis (n=8), onycomycosis (n=4), pityriasis versicolor (n=24) and mucocutaneous candidiasis (n=7). There was significant relation between age and the incidence of skin diseases in RTRs. The incidence of HPV infections, tinea versicolor and premalignant and malignant lesions increased with the duration of immunosuppression. The incidence of infectious skin diseases, especially HPV infections and pityriasis versicolor, was higher in the study group than in the control group. we observed that cutaneous lesions, especially those caused by infectious diseases, had a higher frequency in RTRs. The findings emphasize the regular dermatological screening in these patients to obtain an early diagnosis and treatment.