Atherosclerosis and cardiovascular disease are the main cause of mortality and morbidity in patients with kidney transplants. CIMT is a good measure of atherosclerosis in both in normal population and ESRD patients. We followed a group of kidney transplanted patients for a period of 6 months to evaluate their change of atherosclerosis status. B-mode sonography was performed in each patient to evaluate the carotid IMT at 12 different points: right and left common carotid, carotid bulb and internal carotid. The mean of the 12 points regarded as the CIMT. The baseline measure for CIMT was 0.83±0.22 mm. the measure increased after 2,4 and 6 months intervals after the transplantation and reached to 0.83±0.22 (p=NS), .86 ± 0.23 (p=0.012) and 0.85±0.18 (p=0.003), respectively. the results here shows that the atherosclerosis is an early event after kidney transplantation. The changes in CIMT were significant after 4 months post transplant. Interventions to reverse or slow this process should be taken into account as soon as possible to prevent the long-term morbidity and mortality in kidney transplanted patients.