Renal transplantation model is very complex. For a continuous progress in every models, continuous monitoring is necessary. In this study, we tried to have a closer look at the consequences of the current model of kidney transplantation in Iran. Materials and method: We used the DAPTA (Dialysis And Transplant patients Public Association) data of all kidney transplantations performed in Iran from 1986 to 2005. Our analysis included kidney donors’ and recipients’ data (including demographic and clinical findings). The number of kidney transplantations increased from 98 in 1986 to 1779 in 2005. In this period, the female to male ratio in donors decreased from 1.70 to 0.22. In recipients, this ratio increased from 0.48 to 0.52. The mean age of recipients increased from 27 to 40. From 1986 to 1991, the mean age of donors showed an abrupt decrease from 38 to 28 and then remained constant until 2006. Diabetes mellitus (DM) and hypertension, as the causes of ESRD, took account for less than 1% and 1.9% of all causes in 1986, while they increased after that and reached to 11.4% and 16% in 2005, respectively. Some findings of this study like decrease in female donors, equal access of either genders to transplantation, increase in age of recipients and decrease in the age of donors could be attributable to the progress of the system itself. Some others like increase in the number of transplants, increase in proportion of DM and HTN are attributable to global trend.