Herein we present our experience with both deceased donor Liver Transplanation (DDLT) and living-donor Liver Transplantation (LDLT). Between April 2001 and August 2006, 106 LT procedures were performed (63 DDLTs and 43 LDLTs) in 102 patients (4 retransplants). The overall male/female ratio was 56/46, adult/pediatric ratio was 92/10, and median age 43 years (range, 5-63 years). In the DDLT group; and after a median follow-up period of 724 days (range, 10-1899), the overall patient and graft survival rates was 89%. Deaths were due to primary non-function in 2 patients, central pontine myelinolysis in one patient, chronic rejection in one patient, and recurrent HCV infection in 3 patients. In the LDLT group; and after a median follow-up period of 529 days (range, 8-1354, the overall patient and graft survival rates were 88% and 79% respectively. Graft failure and deaths were due to hepatic artery thrombosis in 2 cases, biliary complication in one patient, uncontrollable bleeding in one patient, portal vein thrombosis in 2 cases, and small-for-size-syndrome in 3 patients. Four patients were successfully re-transplanted using cadaveric organs. Graft survival was significantly inferior in the LDLT group compared with the DDLT group, 79% vs. 89% respectively (p-value <0.05), however, there was no significant difference in patient survival between the two groups.Biliary complications were significantly higher in the LDLT group compared with the DDLT group, 23% vs. 4% respectively (p-value <0.05). Both DDLT and LDLT are being successfully performed at KFSH&RC with good outcomes. Our early experience indicates poorer graft survival and higher rate of biliary complications in the LDLT group.