Management of kidney transplantation's complications is ofen more difficult than kidney transplantation. We managed urological complications of kidney transplantation in 1000 recepient. Between may 1994 and may 2006, 1000 cases of kidney transplantation from cadaver and living kidney donor were performed in two academic hospitals. Urological complication was evaluated with ultrasonography, radionucloide scan and sometime retrograde ureterography in routine follow up or symptomatic patients. Complications included: Vesicoureteral reflux (VUR), vascular anastomosis stricture, urinary stone, urinoma and lymphocele. 28 patients (2.8%) had urological complications. 18 patients (64.28%) of them cured with percutaneus, endourological and laparoscopic approach. (ESWL, PCNL, uretreroscopy and percutaneas nephrostomy). 10 patients (35.72%) selected for open surgery approach. Ureteral necrosis occurred in 5 patients that treated with ureteroureterostomy and native nephrectomy in 3 patients and Boari flap anastomosis was performed for 2 patients. 2 patients with urinary lithiasis and resistant to ESWL and ureteroscopic managements were diagnosed. PCNL was performed for one. And another patients had multiple renal stone and multifocal bone fracture in her limbs and sever osteoprosis. Because of ESRD and resistant urinary lithiasis, transplanted kidney nephrectomy was the best choice for her. 3 patients (0.3%) had vesicoureteral reflux (VUR) that one of them had neuropathic bladder and augmentation cystoplasty was performed for him. Teflon injection and anti reflux surgery were the others approach for next patients. High experience transplantation group and use of imaging study such as ultra sonography, radio nudoid scan and retrograde ureterography can improve results of urological complication of kidney transplantation managements but watch full waiting and close observation had good results in this patients.