Post transplant hyperlipidemia is a risk factor for cardiovascular disease and may also causes chronic allograft nephropathy. There are many reports of this issue in adults but numbers of studies in children are limited. Some of the important contributing factors of post transplant hyperlipidemia include preexisting hyperlipidemia, medications, male gender, and allograft dysfunction. In a cross-sectional design, 12 hour fasting serum triglyceride (TG) and cholesterol (CHO) levels were measured in a group of children with normal renal function 1 to 13 years following kidney transplantation. There were 71 children, 45 males, 26 females with mean age at transplantation of 12.6+/-3.2 years (range,3-19), and a mean follow up of 4+/-2.4 years Sources of donor were living-related (n=24, 33.8%), livingunrelated (n=13, 18.3%) and cadaveric (n=34, 47.9%). Sixty-nine (97.1%) of them were on triple immunosuppressive therapy (cyclosporine+ prednisolone+ cellcept or azathioprine), one was on double therapy, and one didn't use any medication. Mean triglyceride and cholesterol levels were 147+/-51 (range, 65-298) and 185+/-35 (range, 128-275) mg/dl. In most of our cases, TG and CHO level was more than 95th percentile of their standard age and sex values. Mean TG levels were 149+/-50 and 143+/-53 mg/dl among males and females, respectively (P>0.05). Furthermore, mean CHO levels were 180+/-32 and 194+/-40 in males and females, respectively (P>0.05). These levels were highly correlated with the percentile of BMI rather than other parameters such as cyclosporine levels, C0, C2, dose of prednisolone, etc. Hyperlipidemia is common among children who are long-term survivors of our kidney transplants, which should be detected and treated appropriately in post transplant follow up visits.