Renal arterial spasm secondary to manipulation of renal artery is one of complications of live donor nephrectomy. The aim of this study is to determine weather it is necessary to wait for reversal of normal renal consistency and resumption of urinary flow before nephrectomy This study was conducted on 12 of 137 cases of live donor nephrectomy that developed renal arterial spasm. Treatment started by intra arterial injection of 40 m.g papaverin. In 7 cases we wait for reversal of renal arterial spasm, by observation of renal consistency and resumption of urinary flow before nephrectomy (mean,12 min), and in 5 cases we continued toward nephrectomy. We compared early graft function immediately after circulation started in the graft. The early graft functions as shown by immediate urinary flow and normal renal consistency did not show any difference in two groups and was 100% in both. We could show, it might not be necessary to wait for reversal of renal arterial spasm before live donor neprectomy. But to confirm these results, we need further investigation with larger number of cases.