The shortage of donor organs is the primary issue limiting success in the field of organ transplantation. Several approaches have been taken to maximize donor organ capture, including expanding the criteria that define a suitable organ and increasing donor consent through public education efforts. The aim of this study is evaluation of Ahwaz people opinions about donation after brain death. Study papulation was Ahwaz citizens of whome four thousads was selected by random cluster sampling. 68.3 percent of samples were male and 31.7 percent were female. 75 percent were agreeing and 22 percent were opposed and 3 percent had no any opinions about donation after brain death. Age, gender and job had no any effect but nationality, level of education, socio economic status and having a person in their family who needs organ transplantation, were the factors that increased attitudes of people about organ donation after brain death (P<0.05). For increasing consent of organ donation after brain death, increasing the level of general education and improvement in socioeconomic status and financial reimbersment will be helpful.