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Volume: 4 Issue: 2 December 2006 - Supplement - 1

FULL TEXT

CERVICAL CARCINOMA IN KIDNEY TRANSPLANT RECIEPIENTS IN TRANSPLANT CENTER IN GOLESTAN HOSPITAL

Kidney transplant recipients are more predisposed to malignancy. Malignancies are the important causes of mortality in this group. Prevalence of malignancy in transplant patients is 100 times more common than general population. Genitourinary malignancies specially women genital tract are among the most prevalent after transplant. The perpose of this study is evaluation of cervical cancer prevalence in kidney recipient patients. All of the maried female patient undergoing kidney transplant from 1988 to 2003 are accounted in this study. 81 patients were under triple immunosuppressive regimen and 4 were treated with two agents. With maintaining the necessary criteria, after taking history and GU tract physical examination, papsmear was prepared. Cytology results were reported according to bethesda system. 85 patients with mean age of 39 years and average of 5 years after transplant were accounted in this study. No tum lesion of vulvovaginal region was seen in physical examination. In 50 patients cervix was normal and there was athrophy in 18, acute cervicitis in 5, polipoid lesion on exocervix of one patient and the remainders had some evidence in favor of chronic cervicitis. Papsmear was normal in 53 and benign reactive changes was seen in 32 and there was not any low or high grade intraepithelial lesion or malignancy. There is a significant difference in prevalence of cervical malignancy in this study according to others that may because of several reasons including fewer number of cases, shorter follow up, less general risk factors than general population and different enviromental, ethnics, genetic factors and viral carsinogens.



Volume : 4
Issue : 2
Pages : 161


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