Infection is a major complication of renal transplantation, thus eradication of any active infection before transplantation is necessary. Cystic hydatidosis is a zoonosis and is a significant public health problem in different areas such as Middle East. The main treatment of hydatid cyst is surgical extraction of cyst but in a few situation chemotherapy is indicated. Immunosupression may allow proliferation of metacestod remnants or proliferation of previously inapparent metastases.In literature review we did not find renal transplantation in hydatid disease. We present a case of end stage renal failure, with a large hydatid cyst in left lung and a small cyst in right lung. Surgical extraction of left lung cyst was performed and then patient was put on chemotherapy with albendazol 400 mg twice a day for two months. Control CT scan were performed, six and twelve months after surgery and no enlargement in cyst size was observed. After this, renal transplantation was performed. One year after transplantation follow up CT scan did not show any enlargement in cyst size or new cyst formation.