Although somatic problems increase by age, some studies have reported better quality of life in some sub-domains of the elderly. Impact of age on the quality of life after kidney transplantation is also controversial. This study aimed to examine the hypothesis of having a poorer quality of life (QOL) among older transplant recipients, in all sub-domains.This cross-sectional study was performed on 165 kidney recipients in Baqiyatallah hospital in 2006. Patients were categorized into three different age groups: Group I (age<40, n= 85), Group II (age 40-49, n=55), and Group III (age≥50, n= 22). All patients were matched for marital status, educational level, history of graft rejection and dialysis after transplantation. Sub-domains of SF-36 including physical health, social function, limitation due to physical health, bodily pain, general mental health, role limitations due to emotional problems, vitality, and general health perceptions were compared in the study groups. Group III, in comparison to other groups, reported a significantly poorer physical health (48.58±12.99, 57.98±12.33, 57.31±11.46, p=0.01), role limitations due to emotional problems (49.12±23.22, 63.03±26.33, 64.36±26.54, p=0.05), physical function (48.94±27.41, 72.69±25.54, 72.14±22.79, p=0.001), and SF-36 total scores (46.79±10.52, 54.77±10.66, 54.09±9.35, p=0.01), but a significantly better general health perception (52.36±9.18, 48.71±12.01, 43.50±14.81, p=0.020). Other QOL sub-domains were not significantly different among groups. This study represents that, older subjects not only have not a poorer quality of life in all sub-domains, but also report a better general health perception. The higher general health perception of older recipients is perhaps due to their better adjustment to chronic diseases. This is against the exclusion of old patients from the list of transplantation, only because of their age.