Begin typing your search above and press return to search.
Volume: 4 Issue: 2 December 2006 - Supplement - 1

FULL TEXT

CALCIUM-PHOSPHORUS AND PARATHYROID AXIS IN RENAL ALLOGRAFT RECIPIENTS

The issue of calcium metabolism is under-addressed amongst the kidney transplant recipients. The aim of the present study was to delineate the status of calcium-phosphorus-parathyroid hormone axis in these patients. In a descriptive, cross sectional study, 20 renal transplant recipients were evaluated. Age, gender, the time after transplantation and body weight were recoded for each patients. The inclusion criteria were age >14 years, good allograft function defined as serum creatinine <1.5 mg/dl for at least 6 months after transplantation. All the patients were on triple immunosuppressive therapy (cyclosporine A, mycophenolate mofetile and prednisolone). 24-hour urine Ca, phosphorus (P), creatinin (Cr) and protein were measured as well as hemoglobin (Hb), serum Ca, P, Cr and intact parathyroid hormone (iPTH) levels. All data are presented in mean +/- SD and statistical analysis was performed using SPSS 11.0 win.The mean age of patients was 43.6 +/- 11.8 years with male:female ratio of 2:3. The mean body weight was 68.77 +/- 11.98 kg and the mean time after renal transplantation was 36.10 +/- 30.35 months. The mean Hb was 13.6+/- 1.8 g/dl. The serum creatinine was 1.1 +/- 0.45 mg/dl. The mean serum iPTH level was 33.16 +/- 14.66 (pg/ml). Serum Ca and P were 8.97 +/- 0.66 and 3.94 +/- 0.74 mg/dl, respectively. Mean 24-hour urine Cr, protein, Ca, uric acid and phosphorous were1026.33 +/- 450.50 mg, 107.35+/- 128.66mg, 92.80+/- 67.15 mg, 462.22 +/- 165.11 mg and 612.50 +/- 257.34 mg respectively. Ca and P metabolism and PTH axis is, more often than not, normal in renal transplant recipients at our center. These data may be useful for clinicians dealing with kidney transplant recipients.



Volume : 4
Issue : 2
Pages : 137


PDF VIEW [1214] KB.