To determine the post transplant positive anti – HCV patients who were negative before transplantation. 2-Does graft and patient survival alter in whom became positive anti HCV? From 1989 –2003, 800 kidney transplantation were performed in our center. 62 anti HCV negative patients were included in this study.
The mean age was 32 years (7- 69) (33.9% female and 66.1% male), and followed for 4 years. Liver function tests and viral markers measurements carried out every three months any.The results were analyzed by statistical package SPSS using Exact, chi square and ANOVA tests. Anti HCV positive was occurred in 8 patients (12.9%), all were confirmed with (RIBA 3) and HCV RNA polymerase reaction. All of them had history of pre-transplant transfusion, and 83 % of them were under hemodialysis for more than 30 months. We found no acute or chronic rejection in Anti HCV positive patients. Two patients (25%) had liver enzymes increase. One anti HCVpositive patient expired .due to acute hepatitis. No chronic hepatitis C were seen. Although, in our study the impact of post - transplant anti HCV positive on graft survival was not significant, but long term evaluation for better prejudice is mandatory, so, we highly recommend evaluation of anti HCV negative patients after kidney transplantation.