Infectious complications after renal transplantation are associated with significant morbidity and mortality. We evaluated the posttransplant complications resulting from infections and their correlations with graft function, immunosuppressive drugs and mortality. In a 2-year period (2002-2004), 179 renal transplantations were performed in our center. 142 of these were studied and followed for 1-year. Immunosuppressive regimen contained cyclosporin A, mycophenolate mofetil and prednisolone. Each patient was assessed on regular visits according to the ward protocol then results of the investigations (Infections and their correlations with age, sex, donor type, creatinine level, acute rejection, immunosuppressive drugs, graft and patient survival) were registered. Overall incidence of infections was 54%. The most common sites of infections were lower urinary tract (42%) and respiratory tract (6%). The most frequent causes of infections were Klebsiella (24%) and Cytomegalovirus (18%). Wound infection occurred in 5% patients. Overall mortality was 7.7%. Infection-related mortality was 3.5% with developing sepsis. Graft loss was seen in 16 (11%)cases, of whom 2 had developed Cytomegalovirus infection, 2 experienced urinary tract infection (UTI) and 5 developed sepsis(expired). Gender had no impact on UTI incidence. Mycobacterial and hepatitis C infections were noticeably low, compared with other studies. This study identifies infections as the cause of morbidity and mortality in post-transplant period. Patients having higher creatinine level and receiving high dosage of drugs at the discharge time are considered as risky cases and should be evaluated more obsessively.