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Volume: 4 Issue: 2 December 2006 - Supplement - 1

FULL TEXT

DECEASED DONOR QUALITIES THAT AFFECT RENAL TRANSPLANTATION OUTCOME

The aim of the study is to evaluate the qualities of the deceased donor that may affect outcome of renal transplantation. This study was retrospectively conducted from the year 2003-2005. The donor qualities includes the age, gender, causes of death, the duration from admission to retrieval of organs, serum creatinine (SCr) and plasma sodium level at admission and at harvesting and the cold ischemia time, correlated to the recipients conditions that includes length of stay in hospital post transplant, delayed graft function, episode of acute rejection and the patient and graft survival. A total of 253 renal transplantation from 133 deceased donors were performed. The mean age was 31 years with the SCr mean of 101.1µmol/L at admission and 150µmol/L at harvesting. The mean follow up period for recipients was 13 months with an active graft of 85.4% (216 cases), delayed graft function in 34.4% and 19.4% had an episode of acute rejection. The graft survival at one, two and three years was 89%, 78% and 68% respectively, while the patient survival at 3 years was 95%. The age, causes of donors death, the SCr and plasma sodium at harvesting and the cold ischemia time has significant effects on the recipients SCr post transplant, delayed graft function and the episode of acute rejection when compared. Deceased donors characteristics related to age, causes of death and medical complications affect significantly the renal transplantation outcomes.



Volume : 4
Issue : 2
Pages : 115


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