Experience with anomalous kidney transplantation is limited. Due to higher vascular and urological anomalies, these kidneys are underutilized for transplantation. The aim of this case-report is to familiarize the transplantation teams with anomalous kidney transplantation. The first case: A 32-year-old brain dead man was selected for organ donation. Abdominal exploration revealed a horseshoe kidney with good isthmus parenchyme, two arteries, one vein, and one ureter on each side. It was harvested en block and by cutting the isthmus, it was divided into two parts on back table. Then two parts were transplanted in two separate recipeints. The second case: A 29-year-old brain dead man was selected for kidney donation. Abdominal exploration revealed a lump kidney on left lumbar area with four arteries, a main renal vein and 2 accessory small veins, and two ureters. It was harvested en block and transplanted, two arteries were anastomosed together and then to aorta. Another artery was anastomosed to external iliac artery and other to internal iliac artery. Main renal vein was anastomosed to external iliac vein, and other small veins were legated. The ureters were implanted to bladder separately. After transplantation, two recipients developed adequate urine output and discharged with normal creatinine. The third patient, who received one part of horseshoe kidney, developed ATN and after conservative management, her creatinine returned to normal. Considering organ shortage, the anomalous kidneys can be appropriate for transplantation provided that there is no significant pathology and meticulous attention is paid to technical details.