Cutaneous manifestations in renal transplant recipients are frequent represented mainly by infections and cancerous lesions. However dermatologic lesions secondary to autoimmune diseases are rare. We report a relapse of pustular psoriasis occuring after renal transplantation in a 31-year-old woman with a past history of vitiligo. The patient was on haemodialysis during 2 years for undetermined chronic nephropathy. She received a life related transplant from her brother with total HLA identities. She was maintained on an immunosuppressive regimen with corticosteroids, Azathioprine and Ciclosporine. This latter was replaced by mycophenolate mofetil because of neurotoxicity and Azathioprine was stopped. Thirty one months after renal transplantation, she developped a pustular psoriasis treated by retinoids was not efficient. Reintroduction of azathioprine induced remission.