Laparoscopic living donor nephrectomy (LLDN) for kidney transplantation (KTPL) is performed in increasing grafts while minimizing pain and duration of convalescence for donors. The aim of this study is to present our first clinical experiences for LLDN. We prospectively compared 16 LLDN with 20 conventional open procured for KTPL. The data of laparoscopic versus conventional methods are shown for both groups: Age (years, range): 41(23-61) vs. 43(21-74) Gender (male:female)(%): 37.5:62.5 vs. 25:75 Organ side (left:right)(%): 68.75:31.25 vs. 60:40 Access Route (retro-:transperitoneal)(%): 68.75:31.25 vs. 95:5 The results for compared data (mean and range) of laparoscopic versus conventional methods are: Operation time(min): 220(155-361) vs. 124(78-152) Cold ischemia time(min): 165(76-290) vs. 118(39-135) Length of artery(cm): 3.1(0.7-3.9) vs. 3.52(1.5-4.2) Length of vein(cm): 3.6(1.0-4.8) vs. 4.35(1.9-5.3) Hospitalization(days): 6.1(4-10) vs. 4.2(3-5) All recipients in our laparoscopic group are in healthy condition with stable renal function. The hospitalization period and rehabilitation time was shorter for laparoscopic group. Compared to open surgery, the laparoscopic approach results in decreased morbidity, and earlier return to work, with a comparable long-term graft function. LLDN may offer some advantages because of its minimally invasive nature, however, higher costs and longer operative time mandate an individualized choice of this technique.