The purpose of this study is to evaluate blood sugar before and after kidney transplantation. The effects of diabetes on function of transplanted kidneys, patient survival and high blood sugar complications have also been studied. 640 – kidney transplantation has been performed in our center (1989 – 2001). 250 patients have been studied retrospectively for approximately 6 years. Pre and postoperative blood sugar, immunosuppresive medications, familial history of diabetes mellitus, pre and postoperative diabetic induced complications. Transplanted kidneys function and patient survival were evaluated. 23(9%) of 250 patients had high blood sugar, among them diabetes has been the etiology for end stage renal disease in 11(4.4%) patients, (8 cases of IDDM and 3 cases of NIDDM) 12 (4.8%) patients had normal blood sugar before transplantation but developed diabetes thereafter. In patients who had IDDM before transplantation but developed diabetes thereafter.
In patients who had NIDDM (3 cases) the mean blood sugar before and after transplantation were 135 mg/dl and 190 mg/dl respectively. Both cases witched with IDDM after transplantation, which was controlled with average of 50 IU/day Insulin. The mean creatinine level postoperatively, was 1.5 mg/dl. In patients who developed diabetes post transplantation (12 cases). There was familial history of DM in 3 cases, the mean blood sugar before and after transplantation were 107 mg/dl and 190 mg/dl respectively. The mean Creatinine level was 1.4 mg/dl. In conclusion, I) In DM patients Insulin dosage increases after transplantation, II) Renal transplantation can switch NIDDM to. IDDM, III) Transplantation can induce DM in non diabetic patients, IV 7Acute kidney rejection, creatinine level, blood sugar and mortality are higher in diabetic patients.