Kidney transplantation is the treatment of choice for end stage renal disease. With good function, transplanted patients have 25% more survival compared to similar ones who are under dialysis. Episodes of Kidney dysfunction occur in 50-70% of transplant recipients and biopsy is the gold standard to find its causes. If the severity of injury in pathologic reports defines as standard and semi-quantitative manner, the unification of these reports and their comparison will be achieved. In this study categorization of transplanted kidney biopsies according to Banff-97 Classification with respect to their clinical course was aimed. The specimens of three years (1378-1380) were classified as mentioned and clinical data have taken from their past medical reports. From 62 biopsies taken from transplanted patients, 46 have the criteria for adequacy of specimens. The majority (31) of fall into no-rejection or borderline groups. The number of cases in other groups was from 0 to 5.
Treatment response, based on decrease in creatinine level, mean cyclosporine level of each grade, mean creatinine level of each (when the patient was admitted), the induction and rejection therapy protocols were determined. From the discussed items, the difference of treatment response within several Banff grades was accepted meaningful with desirable P-Value. So it seems helpful to categorize the biopsy specimens in such manner.