Due to the increasing number of orthotopic liver transplantations being performed and the availability of well established surgical techniques and immunosuppressive and supportive therapy protocols, the survival expectancy for orthotopic liver transplant (OLT) recipients and their allografts has improved. As a result, the number of OLT recipients requiring elective or emergency nontransplant surgeries is increasing. The aim of this retrospective study was to evaluate perioperative management of OLT recipients who underwent nontransplant surgery at Baskent University Hospital and to evaluate their postoperative graft function. The charts of 106 OLT recipients who received their grafts between December 1988 and July 2004 were reviewed. Among them, 41 patients who underwent nontransplant surgeries were studied. Clinical and demographic data of these patients were analyzed. The 41 patients had undergone 49 nontransplant surgeries. The mean interval between liver transplantation and first surgeries of the patients were 352.0 ± 527.7 days. Thirty-two operations (65.3%) were related to transplantation and 17 (34.7%) were not. Most of the procedures were performed by general (61.2%), gynecologic (12.2%), ear-nose-throat (8.2%) and cardiovascular (8.2%) surgeons. General (83.7%), local anesthesia (8.2%), sedoanalgesia (6.1%), and regional anesthesia (2%) were used. Anesthetic induction was achieved using thiopental (60.6%) and fentanyl (83.3%). Isoflurane (67.3%) along with N2O was used to maintain anesthesia. To provide muscle relaxation and to facilitate intubation either vecuronium (51.7%) or atracurium (34.5%) was given. Additional doses of steroids were given in 72.1% of the cases. No deterioration in early postoperative functional tests of liver and kidney was observed. Orthotopic liver transplant recipients can undergo nontransplant surgeries without postoperative graft dysfunction as long as hepatic perfusion is maintained with appropriate anesthetic management.