The demand for Organ Transplantation has been rapidly increasing because of the increasing success and the rising incidence of End Stage failure of vital organs, while the supply of organs from optimal donors has remained low and insufficient to meet the need. As a result, the number of patients dying each year while on the waiting list is some 10-30% according to the type of organ.
One of the practical solution for this problem is to increase the utilization of Suboptimal or Marginal Donors which are being discarded by many centers.
Suboptimal Donor organs have been successful used by ourselves for the past 20 years, including elderly donors, pediatric donors, diabetic donors, cadaver organs with long preservation time, non-heart beating donors, organs with vascular and anatomic anomalies and ABO incompatible donors.
In this presentation, we will review the result of our experience and that of other centers in the successful used of marginal organs, in the Middle East and USA. Indeed, the use of such marginal donors has the potential of increasing the supply of organs for the treatment of patients with End Stage organ failure by 25-30%, thus making more organs available to a larger number of patients who are currently on the rapidly expanding National Transplant waiting lists all over the world.