Figure 3. Balb/c-WT hearts were grafted into fully mismatched C57BL/6-WT recipients, in which allogeneic responses were induced. Compared with naive C57BL/6-WT, CD4+/CD8+ T-cell ratio, in either traditional or modified transplant models, was similarly shifted (13.7%/6.78% vs 11.4%/5.12%).