Long-term immunosuppressive treatment for adequate graft function results in suppression of the antitumoral function of the immune system and seems to attendant the generally increased risk of various tumors especially non-melanoma skin cancers (NMSCs). In view of this, we conducted a descriptive study to assess clinical and histological features of nonmelanoma skin tumors in 7850 recipients who received allografts in 6 transplant centers between 1984 and 2007. NMSCs were found in 0.4% (n=33) of the renal transplant recipients, among them the most common types were Squamous cell carcinomas (22 cases, 66.6%), and Basal cell carcinomas (11 cases, 33.3%). The patients consisted of 25 men and 8 women with a mean age of 51 (range 21-71) years and 6 to 211(mean 55±49) months after their transplantation. This large experience indicates that in our setting of kidney transplantation, Squamous-cell carcinoma is the most common kind of NMSCs. Early diagnosis and prompt wide local resection of these tumors are required in order to prevent morbidity and mortality in these patients.
Volume : 6
Issue : 4
Pages : 212
Nephrology & Urology Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran