This is a retrospective case-note review study investigating the outcome of 234 pregnancies in 140 renal transplant recipients from five different Middle Eastern countries. 74.4% of the pregnancies were successful albeit with high prevalence of pre-term and Caesarean section deliveries (40.8% and 53 % % respectively.) The mean serum creatinine did not significantly rise during pregnancy in the group as a whole but did so in patients who had serum creatinine of 150umol/L or higher at the beginning of their pregnancies .The mean birth weight was (2458 gms) with 41.3% of the newborns being of low birth weight (<2500 gms). The prevalence of stillbirths were 7.3% and of spontaneous abortion was 19.3 %. Pre-eclampsia and gestational diabetes were observed in 26.1% and 2% of pregnancies respectively. In conclusion, The presence of good allograft function the majority of pregnancies in renal transplant recipients have a good outcome but with increased incidence of pre-eclampsia, reduced gestational age and low birth weights. Patients with baseline serum creatinine of above 150 umol/L have an increased risk of allograft dysfunction resulting from pregnancy.
Volume : 6
Issue : 4
Pages : 2
1King Abdulaziz Medical City, Riyadh, Saudi Arabia, 2Riyadh Armed forces Hospital, Riyadh, Saudi Arabia, 3Jeddah Kidney Centre, Jeddah, Saudi Arabia, 4Royal Hospital, Muscat, Oman,5Rizk Hospital, Beirut, Lebanon, 6King Abdulaziz Hospital, Jeddah, Saudi Arabia, 7Baþkent University, Ankara, Turkey, 8Al-Mouassat University Hospital, Damascus, Syria, 9Security Forces Hospital, Riyadh, Saudi Arabia 10King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.