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Volume: 6 Issue: 4 November 2008 - Supplement - 1



Lung transplantation is a one of the most sophisticated transplantation procedures. The outcome of the patients is not only related to the procedure itself, but also the pre-transplantation condition of the patients has a great influence on the outcome of the lung transplantation. We describe here the characteristics of patients on our waiting list for lung transplantation. Our data come from the lung transplantation waiting list database at Masih Daneshvari Hospital, Tehran, Iran. Patients’ registry began from September 2000 in our database and there are currently 170 patients in our waiting list. We describe here demographic, primary disease cause, pulmonary function test and other laboratory finding here. From 170 patients on the waiting list, 47(27.6%) are male and 123(72.4%) are female. the mean age of the patients is 40.1 ± 16.7 years. the mean time on waiting list was 1.8 ± 1.5 years. the cause disease is bronchiectasia (n=57;33.3%), COPD (n=38, 22.2%), pulmonary fibrosis (34, 19.9%), primary pulmonary hypertension (25 ,14.6%) , and other causes (17, 9.9%). The mean FEV1, FVC and 6-minute walk test result in different diseases were as follows: COPD: 27 ± 14.2, 33.1 ± 14.7, 267.3 ± 130.3; bronchiectasia: 34.1 ± 14.1, 33.8 ± 14.4, 285.1 ± 121.1; pulmonary fibrosis: 26.4 ± 15.7, 31.5 ± 14.3, 237.5 ± 139.5; primary pulmonary hypertension: 43.1 ± 24.5, 45.8 ± 22.3, 296.3 ± 124.8. In conclusion, the main cause for pulmonary insufficiency in our waiting list was bronchiectasia, followed by COPD and pulmonary fibrosis, which is different from other lung transplantation centers. This is in contrast with other lung transplantation centers where COPD patients, who have better outcome after lung transplantation, constitute the majority of the transplantation candidates. Such differences in lung transplantation candidate characteristics may have a negative impact on the outcome of lung transplantation.

Volume : 6
Issue : 4
Pages : 195

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Transplant Research Center, Massih Daneshvari Hospital, Darabad-Niavaran, Tehran, Iran