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Volume: 6 Issue: 4 November 2008 - Supplement - 1

FULL TEXT

LIVE OR DECEASED DONOR KIDNEY TRANSPLANTATION: A COMPARISON OF RESULTS AND SURVIVAL RATES AMONG IRANIAN PATIENTS

Kidney transplantation is the selective and final treatment of end stage renal failure. For years, live donor kidney transplantation was the only choice but increasing demands and advances in the field of transplantation made the possibility of deceased donor transplantation. Despite the advances in the recent years, deceased donor kidney transplantation is not that much favorable. The aim of this study was to investigate and compare the results and survival rates of kidney transplantation among live and deceased donor ones. To reach the aim of this study, the files of patients who had received a kidney transplant at Shariati Hospital in Tehran, Iran, were reviewed and 50 deceased donor kidney transplant patients (group I) were compared with 50 live donor kidney transplant patients (group II). The patients were matched in each group by the time of transplantation. Gathering the data, a questionnaire was used for each of the patients and finally T and Fisher’s Tests were used to analyze the data by means of the SPSS Software version 15. There were 28 males and 22 females with a mean age of 38 ± 13 years in group I while 26 males and 24 females contained group II with a mean age of 34 ± 14 years. The rejection and graft nephrectomy rates were significantly higher in group I than group II (P=0.01, P=0.02). The first year graft tissue survival rate was higher in group II (P=0.001). The graft tissue survival was significantly lower in patients who needed a kidney biopsy and/or dialysis than other patients (P<0.006). On the other side, the graft tissue survival rate was significantly higher in patients who had a urination volume more than 4200 ml within the first 24 hours of transplantation (P<0.003). There wasn’t any statistically significant difference between the survival rates of patients in the two groups. In conclusion, due to the increasing need of kidney transplantation, comprehensive planning for public education about deceased donor kidney transplantation and introducing the benefits of this kind of transplantation seems necessary.



Volume : 6
Issue : 4
Pages : 187


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Transplant Center, Dr Shariati Haspital, Tehran University of Medical Sciences, Tehran, Iran