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Volume: 6 Issue: 4 November 2008 - Supplement - 1

FULL TEXT

URETER REPLACEMENT WITH NEW XENOGENIC OVINE FOETAL URACHUS DUCT IN DOGS

The ureter as an important part of the urinary system that can be affected by several disorders such as congenital malformations, extensive iatrogenic ureteral obstruction, ureteritis, retroperitoneal fibrosis, trauma, necrosis, calculi, tumors, etc. We wished to determine whether ovine foetal urachus duct will be accepted when used as a ureteral replacement material in other species. The ureters of five adult native dogs were approached through a ventral midline laparotomy incision. A segment of 2-cm midureter was resected unilaterally. The left ureteral segments were replaced ovine foetal urachus duct using 5-0 PDS interrupted sutures. Internal ureteral catheter was left for 6 weeks. The patency of the ureters was assessed by intravenous pyelography (IVP) at 2 and 6 weeks, while inflammation and regeneration were assessed grossly and histologically. All five urachus transplantation were accepted successfully in radiological, macroscopical and histological evaluation. The ovine foetal urachus seems to be an embryonic tissue of extremely low antigenicity and therefore suitable for transplantation.



Volume : 6
Issue : 4
Pages : 142


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