Delayed graft function (DGF), a term employed when a newly transplanted organ does not function efficiently is commonly observed following cadaveric renal transplantation but is very rare after living related transplants. We present a 28 -year-old Lebanese female recipient of kidney from her 60 years old mother, who had DGF following transplantation due to acute tubular necrosis, probably caused by partial allograft arterial thrombosis, which recovered function after 72 days. She underwent a living related kidney transplantation after receiving induction therapy with Baslixmab, There was an initial delay in graft function during which period she was oliguric; the urinary output progressively reduced until she became anuric 3 days post transplantation requiring Hemodialysis. The patient underwent multiple ultrasound of the allograft, which revealed normal sized renal allograft with good cortico-medullary differentiation. Doppler scanning showed a good flow but a high resistance index was demonstrated. Renal allograft biopsy was carried out three times during the course of DGF 3, 18, 50 days post transplant, all revealing severe acute tubular necrosis without rejection. She started showing signs of renal recovery on the 68 day post-transplant when her urinary output progressively improved and her Creatinine level dropped down to 1.3 mg/dl on day 72.
Volume : 6
Issue : 4
Pages : 139
Department of Nephrology, Arab Renal Care Group, Amman, Jordan.