Various immunological, metabolic, and technical factors render pediatric recipients with end-stage renal disease unique from their adult counterparts. In addition, the potential for complications after renal transplantation is far greater in children than in adults. In this study, we retrospectively analyzed 43 pediatric recipients who underwent 45 kidney transplantation at Gazi University Transplantation division years from 1996 to 2007. From 1996 to May 2007, 162 renal transplantations were performed at our institution. Forty-five pediatric kidney transplantation was performed in 43 pediatric patients out of 162. Twenty-two boys and 21 girls; age range, 7 to 17 years. Donors were from cadaver in 16 (35%) and living related in 29 (65%) patients. Long-term follow-up revealed the following morbidities in 3 (7,5%) recipients: lymphocele in 1 (2,5%) patients, graft renal artery thrombosis in 2 (2,5%). Two recipients were died with functioning graft, one because of fungal pneumonia and sepsis and other road way accident during 1-130 months follow-up. Four grafts (8 %) were failed (one for immunological reasons, two for BK virus infection and one for renal artery thrombosis). The overall 1, 5, 10 year graft and patients survival rates were 98%, 95%, 82% and 100%, 98%, 95% respectively for all recipients. For cadaveric transplantations, the overall 1, 5, 10 years graft and patients’ survival rates were 100%, 100%, 93% and 100%, 100%, 93% respectively. Better outcomes for renal transplantation in children may be obtained by strict adherence to precise surgical techniques, better immunosuppressive management, and early diagnosis and effective treatment of complications.
Volume : 6
Issue : 4
Pages : 13
Department of Surgery, Gazi University, Ankara, Turkey