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Volume: 6 Issue: 4 November 2008 - Supplement - 1



Liver transplantation is an accepted, life saving operation applied for end-stage liver-failure patients. Poor psychological status & poor adherence is recognized as a major contribution of morbidity, mortality, decreased quality of life, higher medical cost & over utilization of health care services among transplant recipients. During 1378 to 1386, 170 recipients of liver transplant in Shiraz were chosen. Psychological evaluations were done for detecting any significant psychiatric disorders by a psychiatrist before operation. Pre op diagnosis, sex, age and marital status of recipients before operation and duration of hospitalization, rate of post op infections and total morbidity and mortality after operation were collected by researchers in a questioner. The data was evaluated with SPSS 15 by a statistician. From 170 patients 41.6% were females; the mean age was 32.8 years old and 58.2 were married. In psychological evaluations 26.5% of the patients were depressed, 0.7% had insomnia & restlessness, and cognitive disorders were detected in 1.4% of patients. The greatest rate of depression was detected in patients with autoimmune hepatitis (16.1%) (In aspect of diagnosis), females (1.5 times more than males) in aspect of sex & married patients. Post op hospitalization course was longer in the patients with depression (15 days vs. 28 days P value < 0.005). As whole Post op infections were developed in 8 % of the patents, which was twice more in the patients with pre op depression. There was no significant relation between depression and the rate of mortality. Psychological supports before & after liver transplantation can improve outcome of recipients, decreased the course of hospitalization which may decrease post op infections. So psychological interventions must design to improve mental status of the recipients which may improve the successfulness of these important & life saving operation.

Volume : 6
Issue : 4
Pages : 105

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Transplant Research Center of Shiraz University of Medical Sciences, National Institute for Genetic Engineering & Biotechnology, Tarbiat Modares University, Pathology department of Shiraz University of Medical Sciences, Anatomy department of Shiraz University of Medical Sciences